Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.42 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | SCN4A | P35499 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5721001 | 0.85 | LMNA (0.50) | CYP2C9MEN1KMT2ACYP2D6CYP2C19 | |
| SCHEMBL5721003 | 0.85 | LMNA (0.50) | CYP2C9MEN1KMT2ACYP2D6CYP2C19 | |
| SCHEMBL656899 | 0.85 | GABBR2 (0.47) | CYP2C9MEN1KMT2ACYP2D6CYP2C19 | |
| SCHEMBL7638884 | 0.83 | FFAR1 (0.48) | CYP2C9MEN1KMT2ACYP2D6CYP2C19 | |
| SCHEMBL3382822 | 0.83 | MEN1 (0.44) | MEN1KMT2ATSHRCYP1A2GRM1 | |
| SCHEMBL3864293 | 0.81 | KMT2A (0.42) | MEN1KMT2ACYP1A2CYP3A4GRM1 | |
| SCHEMBL14580268 | 0.81 | MEN1 (0.45) | CYP2C9MEN1KMT2ACYP2D6CYP2C19 | |
| SCHEMBL3864636 | 0.81 | KMT2A (0.42) | MEN1KMT2ACYP1A2CYP3A4GRM1 | |
| SCHEMBL3864299 | 0.81 | KMT2A (0.42) | MEN1KMT2ACYP1A2CYP3A4GRM1 | |
| SCHEMBL10745484 | 0.81 | GABBR2 (0.44) | CYP2C9MEN1KMT2ACYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102786482-A | Akt protein kinase inhibitors | ARRAY BIOPHARMA INC | 2012-11-21 | — | — | CN | disclosed |