Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 3/20 | 0.39 |
| ▸ | LTA4H | P09960 | 3/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | ESRRG | P62508 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Boric Acid SCHEMBL28233693 | 0.84 | ACHE (0.38) | MEN1KMT2AKDM4ELMNACYP3A4 | |
| Boric Acid SCHEMBL28032687 | 0.82 | MEN1 (0.31) | MEN1KMT2AKDM4ECYP3A4 | |
| Boric Acid SCHEMBL27924095 | 0.82 | ALDH1A1 (0.41) | MEN1KMT2ACYP3A4HPGDTSHR | |
| Boric Acid SCHEMBL28885301 | 0.82 | CA1 (0.43) | MEN1KMT2ALMNATYRHPGD | |
| Boric Acid SCHEMBL28167570 | 0.82 | CA1 (0.36) | MEN1KMT2ALTA4HLMNACYP3A4 | |
| Boric Acid SCHEMBL28318217 | 0.80 | CA1 (0.35) | MEN1KMT2ALTA4HLMNACYP3A4 | |
| Boric Acid SCHEMBL28373488 | 0.79 | ALDH1A1 (0.41) | MEN1KMT2ATYRCYP3A4HPGD | |
| Boric Acid SCHEMBL28085810 | 0.79 | SLC2A1 (0.42) | KDM4EESR2CYP3A4HPGDTSHR | |
| Boric Acid SCHEMBL28317847 | 0.79 | PPARG (0.53) | LTA4HELANETSHR | |
| Boric Acid SCHEMBL27908262 | 0.78 | CYP1A2 (0.36) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106132967-A | 4,5,6,7 tetrahydro-pyrazoles being replaced also [1,5 a] pyrimidine derivatives and 2,3 dihydro 1H imidazo [1,2 b] pyrazole derivatives as ROS1 inhibitor | 詹森药业有限公司 | 2016-11-16 | — | — | CN | disclosed |
| CN-102105471-B | Novel compounds useful for the treatment of degenerative and inflammatory diseases | GALAPAGOS N.V. (BE) | 2014-10-15 | — | — | CN | disclosed |
| CN-103987384-A | Pyrrolobenzodiazepines and targeting conjugates | SEATTLE GENETICS INC | 2014-08-13 | — | — | CN | disclosed |
| CN-102105472-B | Novel compounds useful for the treatment of degenerative and inflammatory diseases | GALAPAGOS NV | 2013-04-17 | — | — | CN | disclosed |
| CN-102985422-A | Pyrrolopyridine and pyrrolopyrimidine inhibitors of kinases | ABBVIE INC | 2013-03-20 | — | — | CN | disclosed |