Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.39 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.38 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17022656 | 0.89 | HTR2A (0.56) | HTR2AMAPTSLC22A2SLC22A3CA1 | |
| SCHEMBL3918548 | 0.83 | HTR2A (0.54) | HTR2AALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL24270335 | 0.83 | MAOB (0.47) | MAOBALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL29007602 | 0.78 | RAB9A (0.53) | MAOBALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL29145549 | 0.77 | CYP11B1 (0.44) | ALDH1A1MEN1MAPTKMT2ARAB9A | |
| SCHEMBL30633024 | 0.77 | CYP11B1 (0.44) | ALDH1A1MEN1MAPTKMT2ARAB9A | |
| SCHEMBL8111113 | 0.76 | CYP19A1 (0.47) | HTR2AMAPTRAB9ACA1CA2 | |
| SCHEMBL17500316 | 0.76 | HTR2A (0.42) | HTR2AALDH1A1MAPTRAB9ACA1 | |
| Hydrochloric Acid SCHEMBL9719344 | 0.74 | CYP19A1 (0.46) | HTR2AMAPTRAB9A | |
| Alcohol SCHEMBL16265494 | 0.74 | HTR2A (0.45) | HTR2AMAPTSLC22A2SLC22A3BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103204757-B | Method for synthesizing single-alkyl fluorene | UNIV WENZHOU | 2014-11-19 | — | — | CN | disclosed |
| CN-103012025-A | Alkylation method of fluorene | UNIV WENZHOU | 2013-04-03 | — | — | CN | disclosed |