SCHEMBL17022656

SCHEMBL17022656

c1ccc2c(c1)-c1ccccc1C2Cc1ccc(CC2c3ccccc3-c3ccccc32)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.56
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
GSK3B P49841 1/20 0.41
SLC22A2 O15244 1/20 0.39
SLC22A3 O75751 1/20 0.39
GPR3 P46089 1/20 0.39
MAPT P10636 3/20 0.38
KDM4E B2RXH2 1/20 0.38
GAA P10253 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TDO2 P48775 1/20 0.37
CHRM2 P08172 1/20 0.36
HTR1A P08908 1/20 0.36
ADRA2A P08913 1/20 0.36
CHRM1 P11229 1/20 0.36
DRD1 P21728 1/20 0.36
ACHE P22303 1/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3918548 0.93 HTR2A (0.54) HTR2ACA1CA2MAPTHTR6
SCHEMBL28801710 0.89 HTR2A (0.47) HTR2ACA1CA2SLC22A2SLC22A3
SCHEMBL8111113 0.85 CYP19A1 (0.47) HTR2ACA1CA2MAPT
SCHEMBL17500316 0.84 HTR2A (0.42) HTR2ACA1CA2GSK3BMAPT
Alcohol SCHEMBL16265494 0.83 HTR2A (0.45) HTR2ASLC22A2SLC22A3MAPTTDO2
Hydrochloric Acid SCHEMBL9719344 0.83 CYP19A1 (0.46) HTR2AMAPT
SCHEMBL17500281 0.83 RXRA (0.49) HTR2AMAPT
SCHEMBL17520593 0.83 HTR2A (0.41) HTR2ACA1CA2GSK3BMAPT
SCHEMBL6906352 0.81 EDNRB (0.47) HTR2ACA1CA2MAPTKDM4E
SCHEMBL23626030 0.80 HTR2A (0.39) HTR2AMAPTKDM4EGAAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3385300-B1 RESIN COMPOSITION, STRETCHED FILM, CIRCULARLY POLARIZING PLATE, AND IMAGE DISPLAY DEVICE MITSUBISHI CHEM CORP (JP) 2020-12-30 EP disclosed
US-10732323-B2 Retardation film, circularly-polarizing plate, and image-displaying device NITTO DENKO CORPORATION (JP) 2020-08-04 US disclosed
EP-2910589-B1 RESIN COMPOSITION, STRETCHED FILM , CIRCULARLY POLARIZING PLATE, AND IMAGE DISPLAY DEVICE MITSUBISHI CHEM CORP (JP) 2019-09-11 EP disclosed
EP-3133425-B1 RETARDATION FILM, CIRCULARLY-POLARIZING PLATE, AND IMAGE-DISPLAYING DEVICE NITTO DENKO CORP (JP) 2018-12-19 EP disclosed
EP-3385300-A1 RESIN COMPOSITION, STRETCHED FILM, CIRCULARLY POLARIZING PLATE, AND IMAGE DISPLAY DEVICE Mitsubishi Chemical Corporation (JP) 2018-10-10 EP disclosed
EP-3133425-A1 RETARDATION FILM, CIRCULARLY-POLARIZING PLATE, AND IMAGE-DISPLAYING DEVICE Mitsubishi Chemical Holdings Corporation (JP) 2017-02-22 EP disclosed
US-20170031060-A1 RETARDATION FILM, CIRCULARLY-POLARIZING PLATE, AND IMAGE-DISPLAYING DEVICE NITTO DENKO CORPORATION (JP) 2017-02-02 US disclosed
US-9518150-B2 Resin composition, stretched film, circularly polarizing plate, and image display device MITSUBISHI CHEMICAL CORPORATION (JP) 2016-12-13 US disclosed
US-20150247002-A1 RESIN COMPOSITION, STRETCHED FILM, CIRCULARLY POLARIZING PLATE, AND IMAGE DISPLAY DEVICE MITSUBISHI CHEMICAL CORPORATION (JP) 2015-09-03 US disclosed
EP-2910589-A1 RESIN COMPOSITION, STRETCHED FILM , CIRCULARLY POLARIZING PLATE, AND IMAGE DISPLAY DEVICE Mitsubishi Chemical Corporation (JP) 2015-08-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150247002-A1 RESIN COMPOSITION, STRETCHED FILM, CIRCULARLY POLARIZING PLATE, AND IMAGE DISPLAY DEVICE RAD50, RAD54L, PUF60 HTR2A 1634/4885CA1 4254/4885CA2 4120/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.