Hexane

Hexane

SCHEMBL28801739

CC(C)O.CCCCCC.CCCCO

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.69
SMN1; SMN2 Q16637 1/20 0.65
LMNA P02545 4/20 0.61
TSHR P16473 2/20 0.61
MEN1 O00255 2/20 0.61
KMT2A Q03164 2/20 0.61
HSD17B10 Q99714 1/20 0.61
SPHK1 Q9NYA1 2/20 0.42
THRB P10828 2/20 0.41
CYP2D6 P10635 2/20 0.39
HTT P42858 2/20 0.39
GMNN O75496 1/20 0.39
POLB P06746 1/20 0.39
THPO P40225 1/20 0.39
MTOR P42345 1/20 0.39
BLM P54132 1/20 0.39
KDM4E B2RXH2 1/20 0.39
TP53 P04637 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hexane SCHEMBL8466180 0.97 ALDH1A1 (0.65) ALDH1A1SMN1; SMN2LMNATSHRMEN1
Heptane SCHEMBL457572 0.97 LMNA (0.67) ALDH1A1SMN1; SMN2LMNATSHRMEN1
Butyl Alcohol SCHEMBL5571431 0.97 ALDH1A1 (0.73) ALDH1A1SMN1; SMN2LMNATSHRMEN1
Butyl Alcohol SCHEMBL195732 0.97
1-Hexanol SCHEMBL28179252 0.94 LMNA (0.72) ALDH1A1SMN1; SMN2LMNATSHRMEN1
Butyl Alcohol SCHEMBL14142204 0.94 ALDH1A1 (0.69) ALDH1A1SMN1; SMN2LMNATSHRMEN1
Butyl Alcohol SCHEMBL1440709 0.94 ALDH1A1 (0.69) ALDH1A1SMN1; SMN2LMNATSHRMEN1
Butyl Alcohol SCHEMBL8610852 0.94 ALDH1A1 (0.69) ALDH1A1SMN1; SMN2LMNATSHRMEN1
1-Pentanol SCHEMBL6849410 0.94 SMN1; SMN2 (0.75) ALDH1A1SMN1; SMN2LMNATSHRMEN1
Hexane SCHEMBL28618120 0.94 SMN1; SMN2 (0.75) ALDH1A1SMN1; SMN2LMNATSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114853760-A Preparation method of luccotinib intermediate 南京正大天晴制药有限公司 2022-08-05 CN disclosed