SCHEMBL28801775

SCHEMBL28801775

Nc1cccc(Cl)c1Sc1cc(-c2ccccc2)cc(-c2ccccc2)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.40
HSD17B10 Q99714 2/20 0.40
MAPT P10636 2/20 0.40
KDM4E B2RXH2 2/20 0.40
MEN1 O00255 2/20 0.40
LMNA P02545 2/20 0.40
HPGD P15428 2/20 0.40
KMT2A Q03164 2/20 0.40
USP2 O75604 1/20 0.40
HSP90AA1 P07900 1/20 0.40
GAA P10253 1/20 0.40
ALOX15 P16050 1/20 0.40
ALOX12 P18054 1/20 0.40
HTT P42858 1/20 0.40
TSHR P16473 1/20 0.39
TUBB4A P04350 2/20 0.37
TUBB P07437 2/20 0.37
TUBA3C P0DPH7 2/20 0.37
TUBA1B P68363 2/20 0.37
TUBA4A P68366 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3793122 0.83 TSHR (0.48) ALDH1A1KDM4EMEN1LMNAHPGD
SCHEMBL4763015 0.71 ALDH1A1 (0.47) ALDH1A1HSD17B10MAPTKDM4EMEN1
SCHEMBL29358948 0.71 ALDH1A1 (0.47) ALDH1A1HSD17B10MAPTKDM4EMEN1
SCHEMBL15955878 0.70 ALDH1A1 (0.41) ALDH1A1TSHRTUBB4ATUBBTUBA3C
SCHEMBL3783624 0.67 ALDH1A1 (0.54) ALDH1A1HSD17B10MAPTKDM4EMEN1
SCHEMBL7069272 0.67 ITGB2 (0.54) ALDH1A1HSD17B10MAPTKDM4EMEN1
SCHEMBL27715394 0.67 TSHR (0.56) ALDH1A1HSD17B10KDM4EMEN1LMNA
SCHEMBL24162009 0.66 MEN1 (0.53) ALDH1A1HSD17B10MAPTKDM4EMEN1
SCHEMBL4096798 0.66 TSHR (0.50) ALDH1A1MAPTMEN1LMNAKMT2A
SCHEMBL3781780 0.65 ALDH1A1 (0.52) ALDH1A1HSD17B10KDM4EMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220255020-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-08-11 US disclosed
CN-114853745-A Organic electroluminescent material and device 环球展览公司 2022-08-05 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220255020-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, CHRM1 ALDH1A1 463/4885HSD17B10 1922/4885MAPT 2797/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.