SCHEMBL15955878

SCHEMBL15955878

Nc1c(Cl)cc(Sc2c(Cl)cccc2Cl)cc1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.41
CYP3A4 P08684 1/20 0.41
PTGIR P43119 1/20 0.36
TSHR P16473 1/20 0.34
NR4A2 P43354 1/20 0.34
PDE7A Q13946 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
SOD1 P00441 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2A6 P11509 1/20 0.32
RHEB Q15382 1/20 0.32
DHFR P00374 1/20 0.31
TUBB4A P04350 1/20 0.31
TUBB P07437 1/20 0.31
TUBA3C P0DPH7 1/20 0.31
TUBA1B P68363 1/20 0.31
TUBA4A P68366 1/20 0.31
TUBB4B P68371 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5982030 0.79 CYP3A4 (0.55) ALDH1A1CYP3A4TSHRPDE7ACA1
SCHEMBL15955641 0.79 ALDH1A1 (0.40) ALDH1A1PTGIRSOD1
SCHEMBL15955856 0.77 CYP3A4 (0.42) ALDH1A1CYP3A4TSHRPDE7ACA1
SCHEMBL28715207 0.74 CYP1A2 (0.47) ALDH1A1PTGIRTSHRNR4A2SOD1
SCHEMBL15955642 0.72 ALDH1A1 (0.50) ALDH1A1TSHRPDE7A
SCHEMBL71630 0.71
SCHEMBL28801775 0.70 ALDH1A1 (0.40) ALDH1A1TSHRNR4A2CYP2A6TUBB4A
SCHEMBL15955748 0.69 PGR (0.40) ALDH1A1CYP3A4PDE7ACA1CA2
SCHEMBL15955705 0.69 RHEB (0.41) ALDH1A1CYP3A4TSHRPDE7ARHEB
SCHEMBL3793122 0.69 TSHR (0.48) ALDH1A1CYP3A4PTGIRTSHRNR4A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014126580-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2014-08-21 WO disclosed