Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27898743 | 0.78 | AKR1C3 (0.42) | GSK3BTAS1R3TAS1R1KMT2AALDH1A1 | |
| SCHEMBL28277043 | 0.75 | GSK3B (0.50) | GSK3BKMT2AALDH1A1AKR1C3AKR1C2 | |
| SCHEMBL28833020 | 0.75 | AKR1B1 (0.43) | GSK3BTAS1R3TAS1R1POLBALDH1A1 | |
| SCHEMBL19500067 | 0.74 | RAPGEF4 (0.47) | KMT2APOLBALDH1A1CA1CA2 | |
| SCHEMBL28061511 | 0.73 | F2RL1 (0.49) | KMT2APOLBALDH1A1MEN1MAPT | |
| SCHEMBL27916561 | 0.73 | TUBB1 (0.39) | GSK3BKMT2APOLBALDH1A1PTGS1 | |
| SCHEMBL28091448 | 0.71 | FFAR4 (0.37) | KMT2APOLBALDH1A1MEN1CA1 | |
| SCHEMBL27898713 | 0.70 | KDM4E (0.43) | POLBALDH1A1AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL2381725 | 0.69 | GSK3B (0.49) | GSK3BKMT2APOLBALDH1A1MEN1 | |
| SCHEMBL28091556 | 0.68 | FFAR4 (0.36) | KMT2APOLBALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103038231-A | Modulators of HEC1 activity and methods thereof | TAIVEX THERAPEUTICS INC | 2013-04-10 | — | — | CN | disclosed |