Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 3/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | SHBG | P04278 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30265903 | 0.85 | CA12 (0.43) | TSHRMMP2CA12CA1CA2 | |
| SCHEMBL28848779 | 0.79 | TSHR (0.52) | TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL575193 | 0.75 | TSHR (0.43) | TSHRMMP2MMP1EPHX1MEN1 | |
| SCHEMBL779605 | 0.74 | SHBG (0.40) | TSHRMMP2MMP1CA12CA1 | |
| SCHEMBL575317 | 0.73 | TSHR (0.44) | TSHRMMP2MMP1EPHX1MEN1 | |
| SCHEMBL27769846 | 0.71 | MMP2 (0.42) | MMP2MMP1CA12CA1CA2 | |
| SCHEMBL778681 | 0.71 | CA12 (0.40) | TSHRMMP2CA12CA1CA2 | |
| SCHEMBL28980208 | 0.70 | MMP2 (0.47) | TSHRMMP2MMP1CA12CA1 | |
| SCHEMBL28980209 | 0.70 | MMP2 (0.47) | TSHRMMP2MMP1CA12CA1 | |
| SCHEMBL388425 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102816132-B | Anthracene nucleus base-benzo-aza cyclic cpds and preparation method thereof, intermediate and application | KAIHUI TECHNOLOGY DEVELOPMENT (SHANGHAI) CO., LTD. (CN) | 2015-07-29 | — | — | CN | disclosed |
| CN-102816132-A | Anthracene ring-benzo nitrogen heterocyclic compound and preparation method thereof, midbody and application | KAIHUI SCIENCE & TECHNOLOGY DEV SHANGHAI CO LTD | 2012-12-12 | — | — | CN | disclosed |