Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27702925 | 0.80 | TRPA1 (0.40) | MAPTKDM4EPOLBLMNAHTT | |
| SCHEMBL8319755 | 0.65 | GLA (0.36) | MAPTKDM4EPOLBLMNAHTT | |
| SCHEMBL27390431 | 0.65 | MAPT (0.46) | MAPTLMNAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL3661471 | 0.64 | CMA1 (0.38) | MAPTKDM4EPOLBLMNAHTT | |
| SCHEMBL27844868 | 0.63 | TRPA1 (0.38) | MAPTKDM4ELMNAALDH1A1SMN1; SMN2 | |
| (Z)-1,2-Diphenylethene SCHEMBL7706163 | 0.61 | GLA (0.70) | MAPTLMNAALDH1A1GLASMN1; SMN2 | |
| (Z)-1,2-Diphenylethene SCHEMBL7706161 | 0.61 | GLA (0.70) | MAPTLMNAALDH1A1GLASMN1; SMN2 | |
| SCHEMBL7542602 | 0.60 | ALDH1A1 (0.49) | MAPTKDM4EPOLBLMNAHTT | |
| (Z)-1,2-Diphenylethene SCHEMBL8417390 | 0.59 | GLA (0.67) | MAPTLMNAALDH1A1GLASMN1; SMN2 | |
| (Z)-1,2-Diphenylethene SCHEMBL8903561 | 0.59 | GLA (0.67) | MAPTLMNAALDH1A1GLASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114796470-A | Resveratrol compound and CAR-T cell targeting NKG2D ligand combined preparation of medicine for treating malignant tumor | 深圳宾德生物技术有限公司 | 2022-07-29 | — | — | CN | claimed |