SCHEMBL28802496

SCHEMBL28802496

CC1CC1N(C)C(=O)c1cc(C(N)=O)cc(Br)n1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28802495 0.84 SYK (0.36)
SCHEMBL28802513 0.83 NPC1 (0.41)
SCHEMBL28802529 0.77 BRD4 (0.60)
SCHEMBL1579179 0.69 PARP1 (0.45) L3MBTL1
SCHEMBL19641703 0.66 BRD4 (0.39)
SCHEMBL30647258 0.66 HTR1D (0.34)
SCHEMBL28802455 0.65 BRD4 (0.38)
SCHEMBL3118332 0.65 POLB (0.43)
SCHEMBL14303211 0.63 ALDH1A1 (0.47) L3MBTL1
SCHEMBL18920314 0.62 ALDH1A1 (0.52)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109153646-B Pyridine dicarboxamide derivatives as bromodomain inhibitors 葛兰素史克知识产权第二有限公司 2022-08-02 CN disclosed