SCHEMBL2880274

SCHEMBL2880274

O=S(=O)(O)c1ccccc1Cl.[Na]

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 4/20 0.50
TSHR P16473 3/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
ALDH1A1 P00352 2/20 0.43
GAA P10253 1/20 0.43
HSD17B10 Q99714 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
MYC P01106 1/20 0.42
NFE2L2 Q16236 4/20 0.42
POLB P06746 1/20 0.41
SLC1A3 P43003 1/20 0.41
SLC1A2 P43004 1/20 0.41
SLC1A1 P43005 1/20 0.41
FLT1 P17948 1/20 0.41
FLT4 P35916 1/20 0.41
KDR P35968 1/20 0.41
LMNA P02545 1/20 0.41
TTR P02766 1/20 0.41
AKR1B1 P15121 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL50612 0.98 HSD11B1 (0.47) HSD11B1TSHRSMN1; SMN2ALDH1A1GAA
SCHEMBL30454753 0.98 HSD11B1 (0.47) HSD11B1TSHRSMN1; SMN2ALDH1A1GAA
SCHEMBL3709429 0.95 HSD11B1 (0.46) HSD11B1TSHRSMN1; SMN2ALDH1A1GAA
SCHEMBL6917692 0.95 HSD11B1 (0.46) HSD11B1TSHRSMN1; SMN2ALDH1A1GAA
SCHEMBL6908684 0.95 HSD11B1 (0.46) HSD11B1TSHRSMN1; SMN2ALDH1A1GAA
Water SCHEMBL9360422 0.95 HSD11B1 (0.46) HSD11B1TSHRSMN1; SMN2ALDH1A1GAA
SCHEMBL6913307 0.95 HSD11B1 (0.46) HSD11B1TSHRSMN1; SMN2ALDH1A1GAA
SCHEMBL6908686 0.95 HSD11B1 (0.46) HSD11B1TSHRSMN1; SMN2ALDH1A1GAA
SCHEMBL6918638 0.95 HSD11B1 (0.46) HSD11B1TSHRSMN1; SMN2ALDH1A1GAA
Ammonia Solution, Strong SCHEMBL11794102 0.95 HSD11B1 (0.46) HSD11B1TSHRSMN1; SMN2ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106676594-A Low-cost cyanide-free copper-zinc-tin alloy electroplating solution and copper-zinc-tin alloy electroplating technology thereof 太原工业学院 2017-05-17 CN claimed
CN-111793011-B Styrene sulfone NLRP3 inflammatory corpuscle inhibitor and preparation method and application thereof 山东大学 2021-08-20 CN disclosed
CN-111793011-A Styrene sulfone NLRP3 inflammatory corpuscle inhibitor and preparation method and application thereof 山东大学 2020-10-20 CN disclosed
CN-107381912-A The comprehensive processing method of the sulfonic acid waste water of 1,4 diaminourea 2 江苏华尔化工有限公司 2017-11-24 CN disclosed
CN-107206735-A Reinforced thermoplastic articles, compositions for making articles, methods of making, and articles formed therefrom 沙特基础工业全球技术有限公司 2017-09-26 CN disclosed
CN-104619309-B Hair nursing polymer 帝斯曼知识产权资产管理有限公司 2017-09-08 CN disclosed
CN-107001213-A Preparation method and purification method of organic fluorinated aliphatic compound 财团法人峨山社会福祉财团 2017-08-01 CN disclosed
CN-106676594-A Low-cost cyanide-free copper-zinc-tin alloy electroplating solution and copper-zinc-tin alloy electroplating technology thereof 太原工业学院 2017-05-17 CN disclosed
EP-2460789-B1 METHOD FOR PRODUCING BIARYL COMPOUND SUMITOMO CHEMICAL CO (JP) 2017-04-19 EP disclosed
CN-104245102-B The composite membrane of high performance tape positive electricity and the purposes in nano filtering process thereof 巴斯夫欧洲公司 2016-06-22 CN disclosed
US-4880932-A PLANT GROWTH REGULATORS, HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1989-11-14 US disclosed
US-4844730-A PLANT GROWTH REGULATORS BAYER AKTIENGESELLSCHAFT (DE) 1989-07-04 US disclosed
US-4840661-A Sulphonyliso(thio)urea derivatives and herbicidal use thereof BAYER AKTIENGESELLSCHAFT (DE) 1989-06-20 US disclosed
US-4797484-A REACTING GUANIDINE DERIVATIVE WITH SULPHONYL HALIDE BAYER AKTIENGESELLSCHAFT (DE) 1989-01-10 US disclosed
US-4743294-A N'-(substituted-1,3,5-triazin-2-yl)-N\"-amino-N\"'-(substituted-benzenesulphonyl)-guanidines as herbicides BAYER AKTIENGESELLSCHAFT (DE) 1988-05-10 US disclosed
US-4725305-A PLANT GROWTH REGULATORS BAYER AKTIENGESELLSCHAFT (DE) 1988-02-16 US disclosed
US-4725303-A N'-(substituted-pyrimidin-2-yl)-N\"-amino-N\"'-(substituted-benzenesulphonyl)-guanidines as herbicides BAYER AKTIENGESELLSCHAFT (DE) 1988-02-16 US disclosed
US-4721785-A FOR THE 2-GUANIDINE DERIVATIVE HERBICIDE PRODUCTS BAYER AKTIENGESELLSCHAFT (DE) 1988-01-26 US disclosed
US-4647665-A Preparation of sulphonyliso(thio)ureas and sulphonylisoureas BAYER AKTIENGESELLSCHAFT (DE) 1987-03-03 US disclosed
US-4602938-A N'-(substituted-pyrimidin-2-yl)-N\"-substituted-N\",N\"'-bis-(substituted-benzenesulphonyl)-guanidines as herbicides BAYER AKTIENGESELLSCHAFT (DE) 1986-07-29 US disclosed