Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30454753 | 0.98 | HSD11B1 (0.47) | HSD11B1TSHRALDH1A1GAAHSD17B10 | |
| SCHEMBL50612 | 0.98 | HSD11B1 (0.47) | HSD11B1TSHRALDH1A1GAAHSD17B10 | |
| SCHEMBL6908684 | 0.95 | HSD11B1 (0.46) | HSD11B1TSHRALDH1A1GAAHSD17B10 | |
| SCHEMBL6913307 | 0.95 | HSD11B1 (0.46) | HSD11B1TSHRALDH1A1GAAHSD17B10 | |
| SCHEMBL6908686 | 0.95 | HSD11B1 (0.46) | HSD11B1TSHRALDH1A1GAAHSD17B10 | |
| SCHEMBL3709429 | 0.95 | HSD11B1 (0.46) | HSD11B1TSHRALDH1A1GAAHSD17B10 | |
| SCHEMBL6913968 | 0.95 | HSD11B1 (0.46) | HSD11B1TSHRALDH1A1GAAHSD17B10 | |
| Ammonia Solution, Strong SCHEMBL11794102 | 0.95 | HSD11B1 (0.46) | HSD11B1TSHRALDH1A1GAAHSD17B10 | |
| SCHEMBL2880274 | 0.95 | HSD11B1 (0.50) | HSD11B1TSHRALDH1A1GAAHSD17B10 | |
| SCHEMBL6917692 | 0.95 | HSD11B1 (0.46) | HSD11B1TSHRALDH1A1GAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460789-B1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2017-04-19 | — | — | EP | disclosed |
| US-9079830-B2 | Method for producing biaryl compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-07-14 | — | — | US | disclosed |
| CN-103112874-B | Separating and recovering process for solid wastes | JINGBO AGROCHEMICALS TECHNOLOGY CO LTD | 2014-08-27 | — | — | CN | disclosed |
| CN-103112874-A | Separating and recovering process for solid wastes | JINGBO AGROCHEMICALS TECHNOLOGY CO LTD | 2013-05-22 | — | — | CN | disclosed |
| EP-2460789-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2012-06-06 | — | — | EP | disclosed |
| US-20120123154-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120123154-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | AKR7A2, AOC2, CBR1 | HSD11B1 119/4885TSHR 1160/4885ALDH1A1 35/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.