SCHEMBL28804154

SCHEMBL28804154

CCc1ccc(C=Cn2ccnc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.49
TBXAS1 P24557 5/20 0.46
PDE3B Q13370 2/20 0.46
PDE3A Q14432 2/20 0.46
TP53 P04637 1/20 0.44
CYP17A1 P05093 1/20 0.41
CYP1A2 P05177 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
USP2 O75604 1/20 0.40
LMNA P02545 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C19 P33261 1/20 0.40
QPCT Q16769 1/20 0.39
ALOX5 P09917 1/20 0.38
PTGS1 P23219 1/20 0.38
PTGS2 P35354 1/20 0.38
RAB9A P51151 1/20 0.37
TUBB1 Q9H4B7 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4224997 0.81 TBXAS1 (0.49) MAOBTBXAS1PDE3BPDE3AKMT2A
SCHEMBL7158047 0.78 TBXAS1 (0.48) MAOBTBXAS1PDE3BPDE3ACYP1A2
SCHEMBL8927292 0.78 TBXAS1 (0.48) MAOBTBXAS1PDE3BPDE3ACYP1A2
Hydrochloric Acid SCHEMBL27553888 0.76 TBXAS1 (0.47) MAOBTBXAS1PDE3BPDE3ACYP1A2
SCHEMBL11364719 0.75 MEN1 (0.49) TBXAS1PDE3BPDE3ATP53CYP17A1
SCHEMBL11373900 0.72 TBXAS1 (0.44) TBXAS1PDE3BPDE3ACYP1A2MEN1
SCHEMBL19054880 0.72 MAOB (0.53) MAOBTBXAS1TP53CYP17A1CYP1A2
SCHEMBL21181012 0.72 MAOB (0.59) MAOBTBXAS1TP53CYP1A2MEN1
SCHEMBL19076175 0.71 RAB9A (0.53) MAOBTP53CYP1A2MEN1KMT2A
SCHEMBL27896691 0.70 TBXAS1 (0.48) TBXAS1PDE3BPDE3ATP53CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114835854-A Ionic liquid copolymer and method for preparing cyclic carbonate by using same 中国科学院兰州化学物理研究所 2022-08-02 CN disclosed