Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 5/20 | 0.38 |
| ▸ | CDC7 | O00311 | 5/20 | 0.36 |
| ▸ | BTK | Q06187 | 4/20 | 0.35 |
| ▸ | SLC9A1 | P19634 | 5/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | PLK4 | O00444 | 1/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
| ▸ | PRKCG | P05129 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | PRKACA | P17612 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | MARK3 | P27448 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | FRK | P42685 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27767419 | 0.89 | IDO1 (0.39) | BRD4CDC7BTKMAPK1 | |
| SCHEMBL27767422 | 0.86 | CDC7 (0.47) | BRD4CDC7BTK | |
| SCHEMBL27909795 | 0.86 | CDC7 (0.35) | BRD4CDC7PLK4MAPK13DAPK3 | |
| SCHEMBL27767416 | 0.83 | CDC7 (0.52) | BRD4CDC7BTKJAK2CDK2 | |
| SCHEMBL27788865 | 0.81 | BRD4 (0.40) | BRD4JAK2CDK9 | |
| SCHEMBL27767415 | 0.80 | CDC7 (0.52) | BRD4CDC7CDK2 | |
| SCHEMBL27789042 | 0.78 | CASP1 (0.45) | BRD4CDC7PLK4MAPK13DAPK3 | |
| SCHEMBL27789086 | 0.78 | BRD4 (0.44) | BRD4CDC7CDK1CSNK1A1GSK3A | |
| SCHEMBL27909732 | 0.78 | JAK2 (0.44) | BRD4CDC7PLK4MAPK13DAPK3 | |
| SCHEMBL4338838 | 0.77 | BRD4 (0.42) | BRD4CDC7BTKSLC9A1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101622229-B | Pyrrole derivatives having ureido and aminocarbonyl groups as substituents | SANTEN PHARMACEUTICAL CO LTD | 2013-02-27 | — | — | CN | claimed |
| CN-101622229-B | Pyrrole derivatives having ureido and aminocarbonyl groups as substituents | SANTEN PHARMACEUTICAL CO LTD | 2013-02-27 | — | — | CN | disclosed |