Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10352511 | 0.78 | CYP19A1 (0.43) | IDO1RAB9ALMNAKMT2ACYP19A1 | |
| SCHEMBL360432 | 0.77 | TLR2 (0.38) | IDO1ALDH1A1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL362014 | 0.76 | HSD17B10 (0.50) | ALDH1A1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL30764047 | 0.76 | HSD17B10 (0.50) | ALDH1A1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL16711719 | 0.73 | MAPT (0.54) | ALDH1A1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL361807 | 0.73 | IDO1 (0.38) | IDO1ALDH1A1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL363067 | 0.73 | NPC1 (0.39) | IDO1ALDH1A1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL18428692 | 0.72 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2LMNAHTR1AMAPT | |
| SCHEMBL5668088 | 0.72 | GPR35 (0.45) | ALDH1A1RAB9ASMN1; SMN2LMNAHTR1A | |
| SCHEMBL9838306 | 0.72 | HTT (0.57) | ALDH1A1RAB9ALMNAHTR1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102971325-A | Compounds for the reduction of beta-amyloid production | BRISTOL MYERS SQUIBB CO | 2013-03-13 | — | — | CN | disclosed |