SCHEMBL28804696

SCHEMBL28804696

Sc1csc(CCCc2ccccc2)n1

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 2/20 0.42
HDAC6 Q9UBN7 2/20 0.42
CYP2D6 P10635 1/20 0.41
NOS1 P29475 2/20 0.40
HTR2A P28223 1/20 0.40
LOXL2 Q9Y4K0 1/20 0.39
IDO1 P14902 1/20 0.39
TAAR1 Q96RJ0 1/20 0.38
ECE1 P42892 1/20 0.38
SIGMAR1 Q99720 1/20 0.37
MAOA P21397 1/20 0.37
DHFR P00374 1/20 0.37
NOS3 P29474 1/20 0.36
NOS2 P35228 1/20 0.36
MAOB P27338 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2583325 0.80 HDAC1 (0.51) HDAC1HDAC6ECE1
SCHEMBL15522839 0.70 HDAC1 (0.55) HDAC1HDAC6
SCHEMBL28353517 0.70 HTR2A (0.64) HDAC1HDAC6HTR2ALOXL2IDO1
SCHEMBL54347 0.69 HTR2A (0.70) HDAC1HDAC6HTR2ALOXL2IDO1
SCHEMBL24075310 0.69 HDAC1 (0.40) HDAC1HDAC6CYP2D6NOS1MAOA
SCHEMBL25714676 0.69 HDAC1 (0.40) HDAC1HDAC6CYP2D6NOS1MAOA
SCHEMBL1809552 0.69 HDAC1 (0.51) HDAC1HDAC6CYP2D6NOS1LOXL2
SCHEMBL29268834 0.67 HTR2A (0.67) HDAC1HDAC6HTR2ALOXL2IDO1
SCHEMBL10831414 0.67 HTR2A (0.67) HDAC1HDAC6HTR2ALOXL2IDO1
Ammonia Solution, Strong SCHEMBL8817973 0.67 HTR2A (0.67) HDAC1HDAC6HTR2ALOXL2IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102936727-A Corrosion inhibitor for closed system TANGSHAN JINSHA WATER TREAT COMPANY LTD 2013-02-20 CN disclosed