SCHEMBL2583325

SCHEMBL2583325

Sc1csc(Cc2ccccc2)n1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 3/20 0.51
HDAC6 Q9UBN7 3/20 0.51
HDAC8 Q9BY41 1/20 0.51
ALDH1A1 P00352 5/20 0.44
RAB9A P51151 4/20 0.44
LMNA P02545 3/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
KMT2A Q03164 2/20 0.44
ECE1 P42892 1/20 0.44
NPC1 O15118 3/20 0.43
CDK5 Q00535 2/20 0.43
CDK5R1 Q15078 2/20 0.43
GAA P10253 2/20 0.43
LTA4H P09960 1/20 0.41
MAPT P10636 3/20 0.41
CALM1 P0DP23 1/20 0.41
ENPP2 Q13822 1/20 0.39
MEN1 O00255 1/20 0.38
CD74 P04233 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28804696 0.80 HDAC1 (0.42) HDAC1HDAC6ECE1
SCHEMBL2056290 0.77 HDAC1 (0.51) HDAC1HDAC6HDAC8ALDH1A1RAB9A
SCHEMBL11052563 0.77 HDAC1 (0.51) HDAC1HDAC6HDAC8ALDH1A1RAB9A
SCHEMBL6848047 0.77 ALDH1A1 (0.61) HDAC1HDAC6HDAC8ALDH1A1RAB9A
SCHEMBL6123166 0.77 HDAC1 (0.55) HDAC1HDAC6HDAC8ALDH1A1RAB9A
SCHEMBL8432354 0.77 HDAC1 (0.51) HDAC1HDAC6HDAC8ALDH1A1RAB9A
SCHEMBL14133319 0.76 ALDH1A1 (0.64) HDAC1HDAC6HDAC8ALDH1A1RAB9A
SCHEMBL5656467 0.74 HDAC1 (0.55) HDAC1HDAC6HDAC8ALDH1A1RAB9A
SCHEMBL10918996 0.74 HDAC1 (0.58) HDAC1HDAC6HDAC8ALDH1A1RAB9A
SCHEMBL10916542 0.74 HDAC1 (0.53) HDAC1HDAC6HDAC8ALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11548012-B2 Process to treat metal or mineral ores and collector composition therefor NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2023-01-10 US claimed
US-20210197210-A1 PROCESS TO TREAT METAL OR MINERAL ORES AND COLLECTOR COMPOSITION THEREFOR NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2021-07-01 US claimed
EP-3600678-B1 PROCESS TO TREAT METAL OR MINERAL ORES AND COLLECTOR COMPOSITION THEREFOR NOURYON CHEMICALS INT BV (NL) 2021-05-05 EP claimed
EP-3697540-A1 PROCESS TO TREAT METAL OR MINERAL ORES AND COLLECTOR COMPOSITION THEREFOR Nouryon Chemicals International B.V. (NL) 2020-08-26 EP claimed
EP-3636346-A1 PROCESS TO TREAT ORES AND COLLECTOR COMPOSITION THEREFOR Nouryon Chemicals International B.V. (NL) 2020-04-15 EP claimed
US-20200048735-A1 PROCESS TO TREAT METAL OR MINERAL ORES AND COLLECTOR COMPOSITION THEREFOR NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2020-02-13 US claimed
EP-3600678-A1 PROCESS TO TREAT METAL OR MINERAL ORES AND COLLECTOR COMPOSITION THEREFOR Nouryon Chemicals International B.V. (NL) 2020-02-05 EP claimed
US-20080308466-A1 Mineral Recovery from Ore LUMSDEN BARRY GRAHAM 2008-12-18 US claimed
EP-1951433-A1 IMPROVING MINERAL RECOVERY FROM ORE Lumsden, Barry Graham (AU) 2008-08-06 EP claimed
WO-2007059559-A1 IMPROVING MINERAL RECOVERY FROM ORE LUMSDEN BARRY GRAHAM (AU) 2007-05-31 WO claimed
US-4414312-A Photopolymerizable polyamide ester resin compositions containing an oxygen scavenger E. I. DU PONT DE NEMOURS & CO. (US) 1983-11-08 US claimed
US-11578210-B2 Asphalt binders containing a glyceride and fatty acid mixture and methods for making and using same FLINT HILL RESOURCES, LP (US) 2023-02-14 US disclosed
US-11548012-B2 Process to treat metal or mineral ores and collector composition therefor NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2023-01-10 US disclosed
EP-3697540-B1 PROCESS TO TREAT METAL OR MINERAL ORES AND COLLECTOR COMPOSITION WITH A DIMERIC NITRILE NOURYON CHEMICALS INT BV (NL) 2022-09-28 EP disclosed
US-20210197210-A1 PROCESS TO TREAT METAL OR MINERAL ORES AND COLLECTOR COMPOSITION THEREFOR NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2021-07-01 US disclosed
US-6548676-B1 Halogenation or sulfonylation of 5-methylol-2-sulfanyl-thiazole derivatives; separation, salt formation SYNGENTA CROP PROTECTION, INC. 2003-04-15 US disclosed
EP-1201662-A1 Preparation of thiazoles Syngenta Participations AG (CH) 2002-05-02 EP disclosed
EP-0946532-A1 PREPARATION OF THIAZOLES Novartis AG (CH) 1999-10-06 EP disclosed
WO-1998027075-A1 PREPARATION OF THIAZOLES NOVARTIS AG (CH) 1998-06-25 WO disclosed
US-3969289-A One-part foamable latex composition GENERAL LATEX AND CHEMICAL CORPORATION (US) 1976-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11548012-B2 Process to treat metal or mineral ores and collector composition therefor AFF4, FFAR4, FUS HDAC1 2007/4885HDAC6 1106/4885HDAC8 2257/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.