Benzo[D]Thiazole

Benzo[D]Thiazole

SCHEMBL28804971

N#Cc1ccccc1.c1ccc2scnc2c1

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.68
HSD17B10 Q99714 1/20 0.68
TSHR P16473 1/20 0.50
KDM4E B2RXH2 2/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
HKDC1 Q2TB90 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
MEN1 O00255 2/20 0.38
MAPT P10636 2/20 0.38
KMT2A Q03164 2/20 0.38
HTT P42858 1/20 0.38
PFKFB3 Q16875 1/20 0.37
ADORA2A P29274 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
MAOB P27338 2/20 0.36
MAOA P21397 1/20 0.36
GRM5 P41594 1/20 0.36
DYRK1A Q13627 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzo[D]Thiazole SCHEMBL28232967 0.88 ALDH1A1 (0.61) ALDH1A1HSD17B10TSHRKDM4ENPC1
Benzo[D]Thiazole SCHEMBL28297144 0.85 ALDH1A1 (0.79) ALDH1A1HSD17B10KDM4ENPC1RAB9A
Benzo[D]Thiazole SCHEMBL2173015 0.84 ALDH1A1 (0.95) ALDH1A1HSD17B10KDM4ENPC1RAB9A
Benzo[D]Thiazole SCHEMBL27353062 0.84 ALDH1A1 (0.95) ALDH1A1HSD17B10TSHRKDM4ENPC1
Benzo[D]Thiazole SCHEMBL7577714 0.84 ALDH1A1 (0.95) ALDH1A1HSD17B10TSHRKDM4ENPC1
Benzo[D]Thiazole SCHEMBL7731546 0.84 ALDH1A1 (0.95) ALDH1A1HSD17B10TSHRKDM4ENPC1
Benzo[D]Thiazole SCHEMBL2884162 0.83 ALDH1A1 (0.76) ALDH1A1HSD17B10KDM4ENPC1RAB9A
Benzo[D]Thiazole SCHEMBL28588044 0.83 ALDH1A1 (0.76) ALDH1A1HSD17B10KDM4ENPC1RAB9A
Benzo[D]Thiazole SCHEMBL27824233 0.83 ALDH1A1 (0.76) ALDH1A1HSD17B10KDM4ENPC1RAB9A
Benzo[D]Thiazole SCHEMBL29466701 0.82 ALDH1A1 (0.91) ALDH1A1HSD17B10TSHRKDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103214428-A Benzothiazole-cyanophenyl compound serving as hydrazine fluorescence probe as well as preparation method and application method of benzothiazole-cyanophenyl compound UNIV ZHEJIANG 2013-07-24 CN disclosed