Benzo[D]Thiazole

Benzo[D]Thiazole

SCHEMBL2173015

c1ccc2scnc2c1.c1ccccc1

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.95
HSD17B10 Q99714 2/20 0.95
NPC1 O15118 3/20 0.47
RAB9A P51151 3/20 0.47
TDP1 Q9NUW8 3/20 0.47
KDM4E B2RXH2 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
HKDC1 Q2TB90 1/20 0.47
DYRK1A Q13627 1/20 0.40
IDO1 P14902 1/20 0.38
RIPK2 O43353 2/20 0.37
TGFBR1 P36897 2/20 0.37
EGFR P00533 1/20 0.37
KDR P35968 1/20 0.37
RIPK3 Q9Y572 1/20 0.37
MAPK1 P28482 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
RIPK1 Q13546 1/20 0.36
MAPK14 Q16539 1/20 0.36
SYK P43405 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzo[D]Thiazole SCHEMBL10847268 0.97
Benzo[D]Thiazole SCHEMBL31388426 0.97
Benzo[D]Thiazole SCHEMBL8430 0.97
Benzo[D]Thiazole SCHEMBL451685 0.97
Benzo[D]Thiazole SCHEMBL900814 0.97 ALDH1A1 (1.00) ALDH1A1HSD17B10NPC1RAB9ATDP1
Benzo[D]Thiazole SCHEMBL5172231 0.95 ALDH1A1 (0.95) ALDH1A1HSD17B10NPC1RAB9ATDP1
Benzo[D]Thiazole SCHEMBL5141989 0.95 ALDH1A1 (0.95) ALDH1A1HSD17B10NPC1RAB9ATDP1
Benzo[D]Thiazole SCHEMBL18549009 0.95 ALDH1A1 (0.95) ALDH1A1HSD17B10NPC1RAB9ATDP1
Benzo[D]Thiazole SCHEMBL9551908 0.95 ALDH1A1 (0.95) ALDH1A1HSD17B10NPC1RAB9ATDP1
Benzo[D]Thiazole SCHEMBL21679998 0.95 ALDH1A1 (0.95) ALDH1A1HSD17B10NPC1RAB9ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115669907-B Prefabricated pot-gas essence and preparation method thereof 天津春发生物科技集团有限公司 2023-11-03 CN disclosed
CN-111886233-A Novel triazolone derivative or salt thereof and pharmaceutical composition comprising the same 柳韩洋行 2020-11-03 CN disclosed
CN-103951631-B A kind of synthetic method of benzoxazole derivative 重庆大学 2017-01-04 CN disclosed
US-8933168-B2 Activators for two part cyanoacrylate adhesives Henkel IP & Holding GmbH (DE) 2015-01-13 US disclosed
CN-102574882-A Metal complexes MERCK PATENT GMBH 2012-07-11 CN disclosed
CN-102498121-A Metal complexes MERCK PATENT GMBH 2012-06-13 CN disclosed
CN-102316724-A Oil-based agrochemical compositions with increased viscosity COGNIS IP MAN GMBH 2012-01-11 CN disclosed
CN-102317847-A LIQUID CRYSTAL ALIGNING AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT NISSAN CHEMICAL IND LTD 2012-01-11 CN disclosed
CN-102316727-A Agricultural compositions COGNIS IP MAN GMBH 2012-01-11 CN disclosed
US-20110196092-A1 ACTIVATORS FOR TWO PART CYANOACRYLATE ADHESIVES LOCTITE (R&D) LIMITED (IE) 2011-08-11 US disclosed
EP-2346956-A1 ACTIVATORS FOR TWO PART CYANOACRYLATE ADHESIVES Loctite (R & D) Limited (IE) 2011-07-27 EP disclosed
WO-2010046412-A1 ACTIVATORS FOR TWO PART CYANOACRYLATE ADHESIVES LOCTITE (R & D) LIMITED (IE) 2010-04-29 WO disclosed
CN-101654442-A 2- (2' -hydroxyphenyl) benzothiazole chelated zinc derivative and preparation method and application thereof UNIV DALIAN TECH 2010-02-24 CN disclosed
CN-100519568-C Tributylstannyl substituted benzopyrene derivative and method for synthesizing same JIANGSU INST OF NUCLEAR MED (CN) 2009-07-29 CN disclosed
CN-101139357-A Tributylstannyl substituted benzopyrene derivative and method for synthesizing same JIANGSU INST OF NUCLEAR MED (CN) 2008-03-12 CN disclosed