Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2880578 | 1.00 | KCNH2 (0.40) | KCNH2KDM4ENPC1MITFTHRB | |
| SCHEMBL5664623 | 0.83 | ALDH1A1 (0.42) | ABCC9ALDH1A1SMN1; SMN2 | |
| SCHEMBL5664620 | 0.83 | ALDH1A1 (0.42) | ABCC9ALDH1A1SMN1; SMN2 | |
| SCHEMBL2887359 | 0.80 | ABCC9 (0.42) | ABCC9 | |
| SCHEMBL2887357 | 0.80 | ABCC9 (0.42) | ABCC9 | |
| SCHEMBL2891555 | 0.76 | KCNH2 (0.47) | KCNH2ABCC9ALDH1A1TSHR | |
| SCHEMBL2891562 | 0.76 | KCNH2 (0.47) | KCNH2ABCC9ALDH1A1TSHR | |
| SCHEMBL2891557 | 0.76 | KCNH2 (0.47) | KCNH2ABCC9ALDH1A1TSHR | |
| SCHEMBL2012416 | 0.72 | KCNA5 (0.39) | KCNH2KDM4ENPC1MITFTHRB | |
| SCHEMBL2012412 | 0.72 | KCNA5 (0.39) | KCNH2KDM4ENPC1MITFTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732929-B1 | TRICYCLIC BENZOPYRAN COMPOUND AS ANTI-ARRHYTHMIC AGENTS | NISSAN CHEMICAL IND LTD (JP) | 2010-10-20 | — | — | EP | disclosed |
| EP-1732929-A1 | TRICYCLIC BENZOPYRAN COMPOUND AS ANTI-ARRHYTHMIC AGENTS | Nissan Chemical Industries, Ltd. (JP) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005090357-A1 | TRICYCLIC BENZOPYRAN COMPOUND AS ANTI-ARRHYTHMIC AGENTS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2005-09-29 | — | — | WO | disclosed |