Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A3 | P48764 | 15/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28325127 | 0.86 | SLC9A3 (0.41) | SLC9A3CYP2D6TSHR | |
| SCHEMBL18098658 | 0.79 | SLC9A3 (0.49) | SLC9A3CHRNA7CYP2D6TSHROPRM1 | |
| SCHEMBL13457953 | 0.79 | SLC9A3 (0.49) | SLC9A3CHRNA7CYP2D6TSHROPRM1 | |
| SCHEMBL27926169 | 0.79 | SLC9A3 (0.48) | SLC9A3CHRNA7CYP2D6TSHROPRM1 | |
| SCHEMBL8165904 | 0.79 | HTR1A (0.54) | SLC9A3CHRNA7TSHR | |
| SCHEMBL8165906 | 0.79 | HTR1A (0.54) | SLC9A3CHRNA7TSHR | |
| SCHEMBL12362862 | 0.79 | HTR1A (0.54) | SLC9A3CHRNA7TSHR | |
| SCHEMBL27203809 | 0.79 | SLC9A3 (0.49) | SLC9A3CHRNA7CYP2D6TSHROPRM1 | |
| SCHEMBL9813868 | 0.75 | SLC9A3 (0.47) | SLC9A3CHRNA7CYP2D6 | |
| SCHEMBL10699110 | 0.75 | SLC9A3 (0.45) | SLC9A3CHRNA7CYP2D6TSHROPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103396402-A | Substituted aminoindanes and analogs thereof and their pharmaceutical uses | SANOFI AVENTIS | 2013-11-20 | — | — | CN | claimed |