Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A3 | P48764 | 16/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13457953 | 1.00 | SLC9A3 (0.49) | SLC9A3CHRNA7TSHRCYP2D6OPRM1 | |
| SCHEMBL13458177 | 0.85 | ACHE (0.46) | SLC9A3OPRM1 | |
| SCHEMBL27926169 | 0.79 | SLC9A3 (0.48) | SLC9A3CHRNA7TSHRCYP2D6OPRM1 | |
| SCHEMBL12362862 | 0.79 | HTR1A (0.54) | SLC9A3CHRNA7TSHR | |
| SCHEMBL8165904 | 0.79 | HTR1A (0.54) | SLC9A3CHRNA7TSHR | |
| SCHEMBL27203809 | 0.79 | SLC9A3 (0.49) | SLC9A3CHRNA7TSHRCYP2D6OPRM1 | |
| SCHEMBL8165906 | 0.79 | HTR1A (0.54) | SLC9A3CHRNA7TSHR | |
| SCHEMBL28806320 | 0.79 | SLC9A3 (0.48) | SLC9A3CHRNA7TSHRCYP2D6OPRM1 | |
| SCHEMBL9813868 | 0.78 | SLC9A3 (0.47) | SLC9A3CHRNA7CYP2D6 | |
| SCHEMBL7951400 | 0.78 | SLC9A3 (0.47) | SLC9A3CHRNA7CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342178-B1 | SUBSTITUTED AMINOINDANES AND ANALOGS THEREOF, AND THE PHARMACEUTICAL USE THEREOF | SANOFI SA (FR) | 2016-09-28 | — | — | EP | disclosed |