Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 14/20 | 0.53 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27934337 | 0.85 | CNR2 (0.53) | CNR2GPR35CA12CA1CA2 | |
| SCHEMBL27915777 | 0.83 | GPR35 (0.54) | CNR2GPR35CA12CA1CA2 | |
| SCHEMBL27934287 | 0.83 | CNR2 (0.53) | CNR2GPR35CA12CA1CA2 | |
| SCHEMBL27915782 | 0.82 | CNR2 (0.52) | CNR2GPR35CA12CA1CA2 | |
| SCHEMBL28805354 | 0.82 | CNR2 (0.66) | CNR2GPR35CA12CA1CA2 | |
| SCHEMBL27915778 | 0.80 | CNR2 (0.50) | CNR2GPR35CA12CA1CA2 | |
| SCHEMBL26603083 | 0.80 | CNR2 (0.73) | CNR2GPR35CA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL26603163 | 0.79 | CNR2 (0.72) | CNR2GPR35CA12CA1CA2 | |
| SCHEMBL27915787 | 0.79 | CNR2 (0.66) | CNR2GPR35CA12CA1CA2 | |
| SCHEMBL27915784 | 0.78 | MAPT (0.60) | CNR2GPR35CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103265517-B | 3-substituted cumarin analog derivative and uses thereof | ZHEJIANG UNIVERSITY (CN) | 2016-01-13 | — | — | CN | disclosed |
| CN-103265517-A | 3-substituted coumarin derivative and use thereof | UNIV ZHEJIANG | 2013-08-28 | — | — | CN | disclosed |