Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2885471 | 0.87 | TSHR (0.43) | THRBTSHRALDH1A1CA1CA2 | |
| SCHEMBL2880897 | 0.85 | TSHR (0.42) | THRBTSHRALDH1A1 | |
| SCHEMBL244964 | 0.76 | THRB (0.46) | THRBTSHRALDH1A1CA1CA2 | |
| SCHEMBL2885572 | 0.75 | TSHR (0.45) | THRBTSHRALDH1A1CA1CA2 | |
| SCHEMBL156553 | 0.75 | THRB (0.44) | THRBTSHRALDH1A1CA1CA2 | |
| SCHEMBL2882858 | 0.75 | TSHR (0.47) | THRBTSHRALDH1A1CA1CA2 | |
| SCHEMBL2883648 | 0.74 | TSHR (0.46) | THRBTSHRALDH1A1 | |
| SCHEMBL2882331 | 0.73 | THRB (0.42) | THRBTSHRALDH1A1CA1CA2 | |
| SCHEMBL2880741 | 0.72 | TSHR (0.53) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL1357125 | 0.72 | THRB (0.49) | THRBTSHRALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7759451-B2 | Fumaric diester copolymer | TOSOH CORPORATION (JP) | 2010-07-20 | — | — | US | disclosed |
| US-20070298247-A1 | Fumaric diester copolymer | TOSOH CORPORATION (JP) | 2007-12-27 | — | — | US | disclosed |