Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2880741 | 0.91 | TSHR (0.53) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL244964 | 0.89 | THRB (0.46) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL2880930 | 0.86 | TSHR (0.41) | TSHRTHRBALDH1A1 | |
| SCHEMBL798599 | 0.83 | THRB (0.44) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL2885572 | 0.82 | TSHR (0.45) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL27932384 | 0.79 | TSHR (0.53) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL156553 | 0.79 | THRB (0.44) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL2882617 | 0.77 | TSHR (0.46) | TSHRTHRBALDH1A1POLB | |
| SCHEMBL2882331 | 0.76 | THRB (0.42) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL4644189 | 0.76 | THRB (0.54) | TSHRTHRBALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7759451-B2 | Fumaric diester copolymer | TOSOH CORPORATION (JP) | 2010-07-20 | — | — | US | disclosed |
| US-20070298247-A1 | Fumaric diester copolymer | TOSOH CORPORATION (JP) | 2007-12-27 | — | — | US | disclosed |