Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SREBF2 | Q12772 | 1/20 | 0.45 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10272933 | 0.83 | KMT2A (0.44) | SREBF2CYP2D6MAPK1MEN1KMT2A | |
| SCHEMBL27942382 | 0.77 | HRH2 (0.70) | SREBF2HRH2HRH3MAPK1ALDH1A1 | |
| SCHEMBL23894193 | 0.72 | SREBF2 (0.48) | SREBF2HRH2HRH3HSD17B10TP53 | |
| SCHEMBL12910170 | 0.71 | CYP1A2 (0.48) | CYP2D6MAPK1MEN1KMT2AHSD17B10 | |
| SCHEMBL28305148 | 0.70 | CTSS (0.44) | SREBF2KIT | |
| SCHEMBL2495475 | 0.69 | KCNH2 (0.48) | ALDH1A1CYP3A4L3MBTL1IDO1GABRP | |
| SCHEMBL13549544 | 0.69 | MAPT (0.55) | MAPK1MEN1KMT2AHSD17B10USP2 | |
| SCHEMBL2410249 | 0.69 | KMO (0.49) | SREBF2ALDH1A1TLR8FAAHNPC1 | |
| SCHEMBL1685607 | 0.68 | KCNH2 (0.52) | HSD17B10ALDH1A1TP53CYP3A4ADORA3 | |
| SCHEMBL10572459 | 0.68 | PDPK1 (0.37) | ALDH1A1CYP3A4CLK4IDO1MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103391935-A | Diaminopyrimidine derivatives and process for preparing same | YUHAN CORP | 2013-11-13 | — | — | CN | disclosed |