Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1994112 | 0.85 | ALDH1A1 (0.51) | KMT2AHTTSMN1; SMN2TDP1POLB | |
| SCHEMBL4811816 | 0.80 | KMT2A (0.75) | KMT2AMAPTMEN1HTTSMN1; SMN2 | |
| SCHEMBL13688395 | 0.75 | KMT2A (0.43) | KMT2AMEN1HTTSMN1; SMN2TDP1 | |
| SCHEMBL28084732 | 0.73 | ELANE (0.49) | KMT2ASMN1; SMN2POLBELANEATM | |
| SCHEMBL10356467 | 0.72 | ESR2 (0.52) | KMT2AMAPTMEN1HTTTDP1 | |
| SCHEMBL10574401 | 0.71 | KMT2A (0.88) | KMT2AMAPTMEN1HTTSMN1; SMN2 | |
| SCHEMBL10782092 | 0.71 | ELANE (0.44) | KMT2AMAPTMEN1HTTTDP1 | |
| SCHEMBL29007554 | 0.70 | CES2 (0.46) | SMN1; SMN2HPGDALDH1A1EPHX1 | |
| SCHEMBL28445719 | 0.70 | STS (0.43) | KMT2AMAPTMEN1HTTSMN1; SMN2 | |
| SCHEMBL13688365 | 0.70 | ALDH1A1 (0.49) | SMN1; SMN2POLBELANEGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102408337-B | (E)-3-[4-(alkoxy)phenyl]acrylate compounds and preparation method and applications thereof | UNIV SICHUAN | 2014-02-19 | — | — | CN | disclosed |