Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | DRD4 | P21917 | 2/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | PHGDH | O43175 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8981923 | 0.77 | KDM4E (0.60) | KDM4EALDH1A1MAPTPOLBHSD17B10 | |
| SCHEMBL29857922 | 0.76 | PLD1 (0.73) | KDM4EALDH1A1MAPTHPGDPOLB | |
| SCHEMBL15800694 | 0.76 | PLD1 (0.73) | KDM4EALDH1A1MAPTHPGDPOLB | |
| SCHEMBL21353591 | 0.76 | — | — | |
| SCHEMBL9639408 | 0.73 | KDM4E (0.59) | KDM4EALDH1A1MAPTPOLBHSD17B10 | |
| SCHEMBL1108651 | 0.72 | KDM4E (0.58) | KDM4EALDH1A1MAPTHPGDPOLB | |
| SCHEMBL16994742 | 0.72 | KDM4E (0.62) | KDM4EALDH1A1MAPTHPGDPOLB | |
| SCHEMBL7488520 | 0.72 | ALDH1A1 (0.59) | KDM4EALDH1A1MAPTHPGDPOLB | |
| SCHEMBL159733 | 0.71 | PLD1 (0.61) | KDM4EALDH1A1MAPTPOLBHSD17B10 | |
| SCHEMBL29904791 | 0.71 | PLD1 (0.61) | KDM4EALDH1A1MAPTPOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103694163-A | Compounds as Potassium Channel Modulators | SHANGHAI SIMCERE DRUG RES CO LTD | 2014-04-02 | — | — | CN | disclosed |