Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.45 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4404018 | 0.87 | IDO1 (0.58) | IDO1CYP3A4CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL6649233 | 0.81 | IDO1 (0.58) | IDO1CYP3A4CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL14489499 | 0.79 | IDO1 (0.75) | IDO1CYP3A4CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL13320411 | 0.78 | IDO1 (0.55) | IDO1CYP3A4CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL28781325 | 0.76 | IDO1 (0.46) | IDO1CYP3A4CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL17758894 | 0.76 | IDO1 (0.47) | IDO1CYP3A4CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL872242 | 0.75 | IDO1 (0.64) | IDO1CYP3A4CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL29483362 | 0.75 | IDO1 (0.64) | IDO1CYP3A4CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL3071130 | 0.75 | IDO1 (0.64) | IDO1CYP3A4CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL1895055 | 0.74 | RXRA (0.35) | CYP3A4CYP11B1CYP11B2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102014900-B | Method of treating cancer using a neuropeptide Y5R (NPY5R) antagonist | UNIV HEALTH NETWORK | 2014-04-02 | — | — | CN | disclosed |