Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28808837 | 0.81 | IDO1 (0.51) | IDO1NR4A2PKML3MBTL1FABP4 | |
| SCHEMBL28947455 | 0.81 | MAOB (0.44) | MAOBSLC1A5TAAR1 | |
| SCHEMBL28809464 | 0.81 | PARP10 (0.50) | IDO1PKMNPC1RAB9AMMP1 | |
| SCHEMBL28808708 | 0.76 | PARP10 (0.45) | IDO1NPC1RAB9AL3MBTL1LMNA | |
| SCHEMBL286760 | 0.74 | IDO1 (0.57) | IDO1NR4A2MAOAMAOBPKM | |
| SCHEMBL28808716 | 0.73 | IDO1 (0.46) | IDO1NR4A2MAOAMAOBNPC1 | |
| SCHEMBL28808693 | 0.72 | CYP3A4 (0.51) | IDO1NR4A2MAOAMAOBMMP1 | |
| SCHEMBL30444619 | 0.71 | ALDH1A1 (0.65) | IDO1NR4A2MAOAMAOBPKM | |
| SCHEMBL9815841 | 0.70 | L3MBTL1 (0.57) | IDO1NR4A2MAOAMAOBPKM | |
| SCHEMBL984297 | 0.70 | L3MBTL1 (0.57) | IDO1NR4A2MAOAMAOBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112079747-B | N-benzyloxy substituted symmetrical oxamide compound and preparation method and application thereof | 浙江工业大学 | 2022-08-16 | — | — | CN | disclosed |