1-Naphthoquinoline

1-Naphthoquinoline

SCHEMBL28808797

c1ccc(-c2ccccc2)cc1.c1ccc2c(c1)ccc1cccnc12

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.60
MAPT P10636 4/20 0.58
CCR1 P32246 4/20 0.58
CCR8 P51685 4/20 0.58
KDM4E B2RXH2 3/20 0.58
SMN1; SMN2 Q16637 3/20 0.58
MMP2 P08253 3/20 0.58
CYP3A4 P08684 2/20 0.58
HTT P42858 2/20 0.58
TP53 P04637 2/20 0.58
CCR5 P51681 2/20 0.58
TSHR P16473 2/20 0.58
GMNN O75496 1/20 0.58
HSP90AA1 P07900 1/20 0.58
CYP2D6 P10635 1/20 0.58
MMP9 P14780 1/20 0.58
ALOX15 P16050 1/20 0.58
NFKB1 P19838 1/20 0.58
MMP8 P22894 1/20 0.58
THPO P40225 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1-Naphthoquinoline SCHEMBL29204424 0.98 LMNA (0.58) LMNAMAPTCCR1CCR8KDM4E
SCHEMBL3193877 0.94 LMNA (0.67) LMNAMAPTCCR1CCR8KDM4E
1-Naphthoquinoline SCHEMBL29533982 0.92 LMNA (0.69) LMNAMAPTCCR1CCR8KDM4E
1-Naphthoquinoline SCHEMBL15106 0.92 LMNA (0.69) LMNAMAPTCCR1CCR8KDM4E
1-Naphthoquinoline SCHEMBL31141994 0.90 LMNA (0.67) LMNAMAPTCCR1CCR8KDM4E
1-Naphthoquinoline SCHEMBL3045500 0.90 LMNA (0.67) LMNAMAPTCCR1CCR8KDM4E
1-Naphthoquinoline SCHEMBL6340901 0.90 LMNA (0.67) LMNAMAPTCCR1CCR8KDM4E
1-Naphthoquinoline SCHEMBL5572864 0.90 LMNA (0.67) LMNAMAPTCCR1CCR8KDM4E
1-Naphthoquinoline SCHEMBL262791 0.90 LMNA (0.67) LMNAMAPTCCR1CCR8KDM4E
1-Naphthoquinoline SCHEMBL6826374 0.90 LMNA (0.67) LMNAMAPTCCR1CCR8KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117658904-A Acidizing corrosion inhibitor, acidizing working solution, and preparation method and application thereof 延长油田股份有限公司杏子川采油厂 2024-03-08 CN disclosed
CN-103601677-A Preparation method of 2-alkylsulfenylquinoline derivative UNIV TSINGHUA 2014-02-26 CN disclosed