Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGK1 | O00141 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 3/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | BRD2 | P25440 | 1/20 | 0.34 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27931687 | 0.90 | SMN1; SMN2 (0.36) | SGK1SMN1; SMN2MAPTPRMT6JAK1 | |
| SCHEMBL12465706 | 0.85 | MAPT (0.39) | MAPTKITALDH1A1TSHRHPGD | |
| SCHEMBL27947959 | 0.83 | HPGD (0.43) | SMN1; SMN2MAPTTYK2JAK2BRD4 | |
| SCHEMBL27947802 | 0.82 | MLKL (0.40) | MAPTBRD4ALDH1A1TSHRHPGD | |
| SCHEMBL28947302 | 0.81 | POLB (0.46) | JAK1BRD4ALDH1A1HPGDHTT | |
| SCHEMBL27931674 | 0.80 | EDNRB (0.46) | MAPTALDH1A1TSHRHPGD | |
| SCHEMBL28947485 | 0.79 | PPARA (0.42) | MAPTCYP17A1HDAC4ALDH1A1TSHR | |
| SCHEMBL12465700 | 0.79 | MAPT (0.48) | SGK1IDO1TDO2MAPTJAK1 | |
| SCHEMBL27947805 | 0.78 | HTT (0.45) | SMN1; SMN2MAPTBRD4ALDH1A1TSHR | |
| SCHEMBL28809589 | 0.76 | KEAP1 (0.47) | MAPTCYP17A1MAP2K4ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103443098-A | Compound as antagonist of lysophosphatidic acid receptor, composition, and use thereof | CUREGENIX INC | 2013-12-11 | — | — | CN | claimed |
| CN-103443098-A | Compound as antagonist of lysophosphatidic acid receptor, composition, and use thereof | CUREGENIX INC | 2013-12-11 | — | — | CN | disclosed |