Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 7/20 | 0.53 |
| ▸ | CLK2 | P49760 | 2/20 | 0.46 |
| ▸ | CLK3 | P49761 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | WNT1 | P04628 | 3/20 | 0.44 |
| ▸ | PIM1 | P11309 | 2/20 | 0.42 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 2/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.39 |
| ▸ | NTRK3 | Q16288 | 4/20 | 0.39 |
| ▸ | NTRK2 | Q16620 | 4/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | PLK4 | O00444 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29754098 | 0.79 | DYRK1A (0.67) | DYRK1ACLK2CLK3MAPTWNT1 | |
| SCHEMBL23534215 | 0.79 | DYRK1A (0.67) | DYRK1ACLK2CLK3MAPTWNT1 | |
| SCHEMBL13183137 | 0.76 | JAK2 (0.44) | DYRK1ACLK2WNT1JAK2TYK2 | |
| SCHEMBL13183135 | 0.76 | DYRK1A (0.47) | DYRK1AWNT1CYP11B2JAK2MAP4K4 | |
| SCHEMBL13183156 | 0.75 | JAK2 (0.61) | DYRK1ACLK2CLK3MAPTNTRK3 | |
| SCHEMBL31472533 | 0.74 | TRPA1 (0.52) | MAPTJAK2JAK1TYK2JAK3 | |
| SCHEMBL25419245 | 0.74 | TRPA1 (0.52) | MAPTJAK2JAK1TYK2JAK3 | |
| SCHEMBL3540306 | 0.73 | ITK (0.43) | METAP2NTRK1NTRK3NTRK2 | |
| SCHEMBL23533911 | 0.72 | DYRK1A (0.59) | DYRK1ACLK2CLK3WNT1 | |
| SCHEMBL23533877 | 0.72 | DYRK1A (0.70) | DYRK1ACLK2CLK3WNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867718-A | Novel indazole derivative and use thereof | 韩国化学研究院 | 2022-08-05 | — | — | CN | claimed |
| CN-114867718-A | Novel indazole derivative and use thereof | 韩国化学研究院 | 2022-08-05 | — | — | CN | disclosed |