Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.54 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.46 |
| ▸ | CHRNA2 | Q15822 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.46 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | HTR3B | O95264 | 1/20 | 0.46 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.46 |
| ▸ | CHRNG | P07510 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24315732 | 0.80 | CYP11B2 (0.54) | CYP11B2CHRNA7CHRNB2CHRNA4HSD11B1 | |
| SCHEMBL594412 | 0.80 | CYP11B2 (0.54) | CYP11B2CHRNA7CHRNB2CHRNA4HSD11B1 | |
| SCHEMBL29384803 | 0.80 | CYP11B2 (0.54) | CYP11B2CHRNA7CHRNB2CHRNA4ALDH1A1 | |
| SCHEMBL594413 | 0.80 | CYP11B2 (0.54) | CYP11B2CHRNA7CHRNB2CHRNA4ALDH1A1 | |
| SCHEMBL13006578 | 0.80 | CYP11B2 (0.54) | CYP11B2CHRNA7CHRNB2CHRNA4ALDH1A1 | |
| SCHEMBL27934928 | 0.79 | HSD11B1 (0.43) | HSD11B1ALDH1A1LMNAMAPTSPR | |
| SCHEMBL7097811 | 0.76 | CHRNA7 (0.50) | CYP11B2CHRNA7CHRNB2CHRNA4HSD11B1 | |
| SCHEMBL14805866 | 0.76 | CYP11B2 (0.50) | CYP11B2CHRNA7CHRNB2CHRNA4HSD11B1 | |
| SCHEMBL7103827 | 0.76 | CHRNA7 (0.50) | CYP11B2CHRNA7CHRNB2CHRNA4HSD11B1 | |
| SCHEMBL19302636 | 0.76 | USP30 (0.53) | CYP11B2CHRNA7CHRNB2CHRNA4HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103539785-A | Cannabinoid receptor modulators | ARENA PHARM INC | 2014-01-29 | — | — | CN | disclosed |