Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.31 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | CPT2 | P23786 | 1/20 | 0.30 |
| ▸ | CPT1A | P50416 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | GALR3 | O60755 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5785855 | 0.97 | — | — | |
| SCHEMBL6668384 | 0.97 | — | — | |
| SCHEMBL7114163 | 0.97 | — | — | |
| Bromide SCHEMBL23501787 | 0.94 | MAPT (0.42) | MAPTSLC22A16ALDH1A1TSHRCHRM2 | |
| Hydrochloric Acid SCHEMBL7035655 | 0.94 | MAPT (0.48) | MAPTSLC22A16ALDH1A1TSHRCHRM2 | |
| Prolonium SCHEMBL1650849 | 0.81 | MAPT (0.50) | MAPTSLC22A16TSHRCHRM2CHRM4 | |
| Prolonium SCHEMBL1649967 | 0.77 | MAPT (0.52) | MAPTSLC22A16ALDH1A1TSHRCHRM2 | |
| Iodide SCHEMBL10703660 | 0.76 | TSHR (0.33) | TSHR | |
| Prolonium SCHEMBL2889745 | 0.74 | MAPT (0.57) | MAPTSLC22A16ALDH1A1TSHRCHRM2 | |
| Prolonium SCHEMBL11723705 | 0.74 | MAPT (0.50) | MAPTSLC22A16TSHRCHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728255-A | Microspheres containing ionic groups and method for producing same | 株式会社德山 | 2022-07-08 | — | — | CN | disclosed |