SCHEMBL2880930

SCHEMBL2880930

C=C(C)C(=O)OCC1(CCC)COC1

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.41
ALDH1A1 P00352 2/20 0.40
THRB P10828 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2882617 0.91 TSHR (0.46) TSHRALDH1A1THRB
SCHEMBL9263705 0.88 TSHR (0.36) TSHR
SCHEMBL6361317 0.88 TSHR (0.51) TSHRALDH1A1THRB
SCHEMBL156498 0.87 ALDH1A1 (0.42) TSHRALDH1A1THRB
SCHEMBL2882858 0.86 TSHR (0.47) TSHRALDH1A1THRB
SCHEMBL9263710 0.83 TSHR (0.34) TSHR
SCHEMBL3462881 0.83 ALDH1A1 (0.37) TSHRALDH1A1
SCHEMBL10581539 0.81 ALDH1A1 (0.43) TSHRALDH1A1THRB
SCHEMBL30775580 0.81 ALDH1A1 (0.46) TSHRALDH1A1THRB
SCHEMBL13610550 0.81 ALDH1A1 (0.40) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7759451-B2 Fumaric diester copolymer TOSOH CORPORATION (JP) 2010-07-20 US disclosed
US-7320854-B2 Mixture of oxide particles, polymerizable compound,radiation sensitive decomposer and releasing agent JSR CORPORATION (JP) 2008-01-22 US disclosed
US-20070298247-A1 Fumaric diester copolymer TOSOH CORPORATION (JP) 2007-12-27 US disclosed
EP-1494072-A2 Radiation sensitive refractive index changing composition, pattern forming method and optical material JSR Corporation (JP) 2005-01-05 EP disclosed
US-20040265737-A1 Radiation sensitive refractive index changing composition, pattern forming method and optical material JSR CORPORATION (JP) 2004-12-30 US disclosed