Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8667004 | 0.76 | GPR119 (0.43) | GPR119NR1H2NR1H3KDM4EPKM | |
| SCHEMBL29103624 | 0.75 | GPR119 (0.41) | GPR119KDM4EPKMUSP30HPGDS | |
| SCHEMBL28139616 | 0.74 | TSHR (0.43) | GPR119NR1H2NR1H3RORCUSP30 | |
| SCHEMBL27704578 | 0.72 | NR1H2 (0.48) | GPR119NR1H2NR1H3KDM4EPKM | |
| SCHEMBL16004573 | 0.72 | NR1H2 (0.53) | GPR119NR1H2NR1H3RORCTSHR | |
| SCHEMBL18642718 | 0.72 | NR1H2 (0.53) | GPR119NR1H2NR1H3RORCTSHR | |
| SCHEMBL28815574 | 0.72 | NR1H2 (0.53) | GPR119NR1H2NR1H3RORCTSHR | |
| SCHEMBL28278882 | 0.72 | GPR119 (0.44) | GPR119NR1H2NR1H3KDM4EPKM | |
| SCHEMBL28765886 | 0.71 | GPR119 (0.47) | GPR119NR1H2NR1H3KDM4EPKM | |
| SCHEMBL15664940 | 0.71 | TSHR (0.43) | GPR119NR1H2NR1H3RORCTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103582482-A | Pharmaceutically active disubstituted triazine derivatives | LEAD DISCOVERY CENTER GMBH | 2014-02-12 | — | — | CN | disclosed |