Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.64 |
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | BLM | P54132 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 5/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.60 |
| ▸ | RELA | Q04206 | 1/20 | 0.60 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16430986 | 0.85 | MAPT (0.74) | MEN1KMT2AMAPTPOLBBLM | |
| SCHEMBL16431063 | 0.82 | MEN1 (0.69) | MEN1KMT2AMAPTPOLBBLM | |
| SCHEMBL3644090 | 0.81 | LMNA (0.58) | MEN1KMT2AMAPTPOLBLMNA | |
| SCHEMBL9329754 | 0.81 | MEN1 (0.85) | MEN1KMT2AMAPTPOLBBLM | |
| SCHEMBL27942778 | 0.81 | PTGS1 (0.67) | MEN1KMT2AMAPTLMNARAB9A | |
| SCHEMBL2851288 | 0.81 | MEN1 (0.75) | MEN1KMT2AMAPTPOLBBLM | |
| SCHEMBL27923735 | 0.81 | MAPT (0.58) | MEN1KMT2AMAPTPOLBLMNA | |
| SCHEMBL1336235 | 0.80 | MEN1 (0.74) | MEN1KMT2AMAPTPOLBBLM | |
| SCHEMBL4996591 | 0.80 | RXFP1 (0.61) | MEN1KMT2AMAPTPOLBBLM | |
| SCHEMBL16441779 | 0.80 | MEN1 (0.69) | MEN1KMT2AMAPTPOLBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103387576-A | Aramide Raf kinase inhibitor based on purine structure and preparation method and application thereof | UNIV CHINA PHARMA | 2013-11-13 | — | — | CN | disclosed |