SCHEMBL9329754

SCHEMBL9329754

O=C(Nc1cccc([N+](=O)[O-])c1)c1ccc(C(=O)Nc2cccc([N+](=O)[O-])c2)cc1

nearest known ligand 0.88

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 9/20 0.85
KMT2A Q03164 9/20 0.85
MAPT P10636 7/20 0.85
POLB P06746 3/20 0.85
BLM P54132 1/20 0.85
SMN1; SMN2 Q16637 5/20 0.81
RAB9A P51151 5/20 0.81
NPC1 O15118 4/20 0.81
LMNA P02545 3/20 0.81
ALDH1A1 P00352 1/20 0.81
NFKB1 P19838 1/20 0.81
NFKB2 Q00653 1/20 0.81
RELA Q04206 1/20 0.81
KDM4E B2RXH2 1/20 0.75
TDP1 Q9NUW8 1/20 0.75
DDX3X O00571 1/20 0.73
HTT P42858 1/20 0.73
CTDSP1 Q9GZU7 1/20 0.73
SETD7 Q8WTS6 2/20 0.69
CYP3A4 P08684 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8710919 0.97 MEN1 (0.80) MEN1KMT2AMAPTPOLBBLM
SCHEMBL9800017 0.94 GAA (0.77) MEN1KMT2AMAPTPOLBBLM
SCHEMBL11572673 0.94 MEN1 (0.76) MEN1KMT2AMAPTPOLBBLM
SCHEMBL6795867 0.94 MEN1 (0.85) MEN1KMT2AMAPTPOLBBLM
SCHEMBL13698359 0.93 MEN1 (0.91) MEN1KMT2AMAPTPOLBBLM
SCHEMBL3138079 0.93 MEN1 (0.74) MEN1KMT2AMAPTPOLBBLM
SCHEMBL1336235 0.93 MEN1 (0.74) MEN1KMT2AMAPTPOLBBLM
SCHEMBL1454159 0.93 MEN1 (0.74) MEN1KMT2AMAPTPOLBBLM
Iodide SCHEMBL30758621 0.92 MEN1 (0.83) MEN1KMT2AMAPTPOLBBLM
SCHEMBL32690121 0.92 MEN1 (1.00) MEN1KMT2AMAPTPOLBBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0193374-B1 Thermoplastic aromatic polyamideimide copolymers and process for their preparation TORAY INDUSTRIES (JP) 1994-04-13 EP disclosed
US-4831104-A MOLDING MATERIALS TORAY INDUSTRIES, INC. (JP) 1989-05-16 US disclosed
EP-0193374-A2 Thermoplastic aromatic polyamideimide copolymers and process for their preparation TORAY INDUSTRIES, INC. (JP) 1986-09-03 EP disclosed