Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 5/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 7/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.42 |
| ▸ | PTPRS | Q13332 | 3/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27941489 | 0.93 | STAT3 (0.42) | STAT3PTPN1PTPN2PTPRSCYP19A1 | |
| SCHEMBL28810587 | 0.91 | PTPN1 (0.44) | STAT3PTPN1PTPN2PTPRSCYP19A1 | |
| SCHEMBL28809687 | 0.80 | STAT3 (0.65) | STAT3PTPN1PTPN2PTPRS | |
| SCHEMBL15559484 | 0.80 | STAT3 (0.53) | STAT3CYP19A1 | |
| SCHEMBL28810537 | 0.79 | STAT3 (0.60) | STAT3PTPN1PTPN2PTPRS | |
| SCHEMBL15559430 | 0.78 | STAT3 (0.53) | STAT3 | |
| SCHEMBL15560941 | 0.78 | STAT3 (0.60) | STAT3 | |
| SCHEMBL12466793 | 0.77 | STAT3 (0.51) | STAT3 | |
| SCHEMBL27941491 | 0.73 | STAT3 (0.65) | STAT3PTPN1PTPN2PTPRS | |
| SCHEMBL28810588 | 0.72 | STAT3 (0.67) | STAT3PTPN1PTPN2PTPRS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103608010-A | Substituted 2-hydroxy-4-(2-(phenylsulfonamido)acetamido)benzoic acid analogs as inhibitors of STAT proteins | UNIV CENTRAL FLORIDA RES FOUND | 2014-02-26 | — | — | CN | disclosed |