Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 6/20 | 0.44 |
| ▸ | PTPRS | Q13332 | 6/20 | 0.44 |
| ▸ | STAT3 | P40763 | 3/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | PKLR | P30613 | 1/20 | 0.36 |
| ▸ | PPIA | P62937 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28809685 | 0.91 | STAT3 (0.42) | PTPN1PTPRSSTAT3PTPN2CYP19A1 | |
| SCHEMBL27941489 | 0.87 | STAT3 (0.42) | PTPN1PTPRSSTAT3PTPN2CYP19A1 | |
| SCHEMBL28810588 | 0.81 | STAT3 (0.67) | PTPN1PTPRSSTAT3PTPN2 | |
| SCHEMBL27952959 | 0.81 | STAT3 (0.62) | PTPN1PTPRSSTAT3PTPN2 | |
| SCHEMBL15559484 | 0.78 | STAT3 (0.53) | STAT3CYP19A1 | |
| SCHEMBL15559430 | 0.76 | STAT3 (0.53) | STAT3 | |
| SCHEMBL15560941 | 0.76 | STAT3 (0.60) | STAT3 | |
| SCHEMBL12466793 | 0.75 | STAT3 (0.51) | STAT3 | |
| SCHEMBL28809687 | 0.72 | STAT3 (0.65) | PTPN1PTPRSSTAT3PTPN2 | |
| SCHEMBL10243372 | 0.71 | STAT3 (0.73) | PTPN1PTPRSSTAT3PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103608010-A | Substituted 2-hydroxy-4-(2-(phenylsulfonamido)acetamido)benzoic acid analogs as inhibitors of STAT proteins | UNIV CENTRAL FLORIDA RES FOUND | 2014-02-26 | — | — | CN | disclosed |