Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 1/20 | 0.60 |
| ▸ | WNT1 | P04628 | 6/20 | 0.59 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.59 |
| ▸ | BACE1 | P56817 | 1/20 | 0.56 |
| ▸ | KDM1A | O60341 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 4/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.48 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
| ▸ | HTR3B | O95264 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29753960 | 1.00 | HTR4 (0.60) | HTR4WNT1DYRK1ABACE1KDM1A | |
| SCHEMBL29753901 | 0.86 | HTR4 (0.56) | HTR4WNT1DYRK1ABACE1KDM1A | |
| SCHEMBL23533891 | 0.86 | HTR4 (0.56) | HTR4WNT1DYRK1ABACE1KDM1A | |
| SCHEMBL10784335 | 0.82 | HTR4 (0.69) | HTR4KDM1AALDH1A1KMT2AHTR3E | |
| SCHEMBL29754003 | 0.81 | DYRK1A (0.86) | WNT1DYRK1AGSK3BKCNH2 | |
| SCHEMBL23535044 | 0.81 | DYRK1A (0.86) | WNT1DYRK1AGSK3BKCNH2 | |
| SCHEMBL29754079 | 0.81 | KDM1A (0.52) | HTR4WNT1DYRK1ABACE1KDM1A | |
| SCHEMBL28809191 | 0.81 | KDM1A (0.52) | HTR4WNT1DYRK1ABACE1KDM1A | |
| SCHEMBL28809209 | 0.80 | HTR4 (0.59) | HTR4WNT1DYRK1ABACE1KDM1A | |
| SCHEMBL29754034 | 0.80 | HTR4 (0.59) | HTR4WNT1DYRK1ABACE1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867718-A | Novel indazole derivative and use thereof | 韩国化学研究院 | 2022-08-05 | — | — | CN | disclosed |