Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | IKBKE | Q14164 | 6/20 | 0.44 |
| ▸ | TBK1 | Q9UHD2 | 6/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | NHERF1 | O14745 | 2/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29754174 | 1.00 | GSK3B (0.50) | GSK3BDYRK1ANTRK1IKBKETBK1 | |
| SCHEMBL29754046 | 0.87 | IKBKE (0.59) | GSK3BDYRK1AIKBKETBK1NR4A2 | |
| SCHEMBL28809188 | 0.87 | IKBKE (0.59) | GSK3BDYRK1AIKBKETBK1NR4A2 | |
| SCHEMBL29754042 | 0.83 | IKBKE (0.51) | GSK3BDYRK1AIKBKETBK1NR4A2 | |
| SCHEMBL28809765 | 0.83 | IKBKE (0.51) | GSK3BDYRK1AIKBKETBK1NR4A2 | |
| SCHEMBL23533876 | 0.82 | DYRK1A (0.71) | GSK3BDYRK1A | |
| SCHEMBL28809170 | 0.81 | IKBKE (0.60) | IKBKETBK1NR4A2ROCK1NHERF1 | |
| SCHEMBL29754041 | 0.81 | IKBKE (0.60) | IKBKETBK1NR4A2ROCK1NHERF1 | |
| SCHEMBL28809217 | 0.79 | IKBKE (0.63) | GSK3BDYRK1AIKBKETBK1ROCK1 | |
| SCHEMBL29753969 | 0.79 | IKBKE (0.63) | GSK3BDYRK1AIKBKETBK1ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867718-A | Novel indazole derivative and use thereof | 韩国化学研究院 | 2022-08-05 | — | — | CN | disclosed |