Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
| ▸ | HBB | P68871 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | TSPO | P30536 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29689953 | 1.00 | KDM4E (0.49) | KDM4EMAPTMAPK1ALDH1A1HPGD | |
| SCHEMBL29690274 | 0.87 | MMP3 (0.51) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL28810411 | 0.87 | MMP3 (0.51) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL16482591 | 0.83 | KDM4E (0.63) | KDM4EMAPTMAPK1ALDH1A1HPGD | |
| SCHEMBL10042911 | 0.83 | KDM4E (0.63) | KDM4EMAPTMAPK1ALDH1A1HPGD | |
| SCHEMBL31027168 | 0.82 | MAPT (0.69) | KDM4EMAPTMAPK1ALDH1A1HPGD | |
| SCHEMBL14805531 | 0.82 | MAPT (0.69) | KDM4EMAPTMAPK1ALDH1A1HPGD | |
| SCHEMBL14805532 | 0.82 | MAPT (0.69) | KDM4EMAPTMAPK1ALDH1A1HPGD | |
| SCHEMBL602352 | 0.82 | MAPT (0.69) | KDM4EMAPTMAPK1ALDH1A1HPGD | |
| SCHEMBL24667910 | 0.81 | KDM4E (0.59) | KDM4EMAPTMAPK1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109970622-B | 2-substituent-3- (9-alkyl-9H-carbazole-3-yl) acrylonitrile compound and preparation method thereof | 陕西科技大学 | 2022-06-07 | — | — | CN | disclosed |