Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 2/20 | 0.51 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | GPR3 | P46089 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HK1 | P19367 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
| ▸ | TSPO | P30536 | 3/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29690274 | 1.00 | MMP3 (0.51) | MMP3BACE1GPR3RXRARXRB | |
| SCHEMBL28810414 | 0.87 | KDM4E (0.49) | MMP3KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL29689953 | 0.87 | KDM4E (0.49) | MMP3KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL2719911 | 0.85 | MMP3 (0.45) | MMP3BACE1TGFBR1 | |
| SCHEMBL17194696 | 0.82 | GPR3 (0.47) | GPR3RXRARXRBKDM4EALDH1A1 | |
| SCHEMBL17904032 | 0.82 | RXRA (0.49) | GPR3RXRARXRBKDM4EALDH1A1 | |
| SCHEMBL17125563 | 0.81 | GPR3 (0.61) | GPR3RXRARXRBKDM4EALDH1A1 | |
| SCHEMBL17194466 | 0.80 | TSPO (0.47) | GPR3RXRARXRBKDM4EALDH1A1 | |
| SCHEMBL10447275 | 0.79 | GPR3 (0.70) | GPR3RXRARXRBKDM4EALDH1A1 | |
| SCHEMBL10331500 | 0.79 | GPR3 (0.70) | GPR3RXRARXRBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109970622-B | 2-substituent-3- (9-alkyl-9H-carbazole-3-yl) acrylonitrile compound and preparation method thereof | 陕西科技大学 | 2022-06-07 | — | — | CN | disclosed |