SCHEMBL28810976

SCHEMBL28810976

CC(=O)NCCCCCC#N

nearest known ligand 0.67

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.67
MAPK1 P28482 1/20 0.67
HIF1A Q16665 1/20 0.67
PAOX Q6QHF9 3/20 0.55
ADRA1A P35348 1/20 0.53
TSHR P16473 1/20 0.40
NAMPT P43490 1/20 0.39
FOLH1 Q04609 1/20 0.39
EPHX1 P07099 4/20 0.39
ALDH1A1 P00352 2/20 0.39
ALDH1A2 O94788 1/20 0.39
ALDH2 P05091 1/20 0.39
ALDH1A3 P47895 1/20 0.39
EPHX2 P34913 1/20 0.38
GBA1 P04062 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11757886 1.00 KDM4E (0.67) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL25050720 0.91
SCHEMBL48475 0.82
SCHEMBL10937726 0.82 KDM4E (1.00) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL1847535 0.82 KDM4E (1.00) KDM4EMAPK1HIF1APAOXADRA1A
Hexamethylenebisacetamide SCHEMBL61980 0.82 KDM4E (1.00) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL14739632 0.82 KDM4E (1.00) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL14740132 0.82 KDM4E (1.00) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL6516953 0.82 KDM4E (1.00) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL1900654 0.82 KDM4E (1.00) KDM4EMAPK1HIF1APAOXADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110423201-B Method for synthesizing hexamethylene diamine by using caprolactam as raw material 郑州大学 2022-07-12 CN disclosed