Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19989638 | 0.89 | PPARG (0.39) | PPARGPPARASIGMAR1KDM4EMMP2 | |
| SCHEMBL19989624 | 0.86 | SIGMAR1 (0.46) | PPARGPPARASIGMAR1KDM4EMMP2 | |
| SCHEMBL19989668 | 0.86 | PPARG (0.45) | PPARGPPARASIGMAR1KDM4EMMP2 | |
| SCHEMBL28810919 | 0.81 | DRD2 (0.44) | PPARGPPARASIGMAR1KDM4EKCNA3 | |
| SCHEMBL19989562 | 0.79 | MAPK1 (0.42) | PPARGPPARASIGMAR1KDM4EKCNA3 | |
| SCHEMBL19989620 | 0.79 | SLC6A2 (0.57) | KDM4EMMP2MMP3 | |
| SCHEMBL28810925 | 0.79 | PPARG (0.43) | PPARGPPARASIGMAR1KDM4EKCNA3 | |
| SCHEMBL19989695 | 0.78 | KDM4E (0.50) | PPARGPPARASIGMAR1KDM4EMMP2 | |
| SCHEMBL28811903 | 0.78 | DRD2 (0.46) | PPARGPPARAKCNA3 | |
| Hydrochloric Acid SCHEMBL28810954 | 0.77 | PPARG (0.40) | PPARGPPARASIGMAR1KDM4EKCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110088087-B | Tetrahydropyridine derivatives and their use as antibacterial agents | 东亚ST株式会社 | 2022-08-09 | — | — | CN | disclosed |