Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.52 |
| ▸ | CPB1 | P15086 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL436604 | 0.98 | ALDH1A1 (0.58) | ALDH1A1NPSR1KMT2AMAPTKDM4E | |
| Hydrochloric Acid SCHEMBL27602135 | 0.96 | ALDH1A1 (0.56) | ALDH1A1NPSR1KMT2AMAPTKDM4E | |
| SCHEMBL12615992 | 0.83 | ALDH1A1 (0.68) | ALDH1A1NPSR1KMT2AMAPTKDM4E | |
| SCHEMBL18378771 | 0.83 | ALDH1A1 (0.54) | ALDH1A1NPSR1KMT2AMAPTKDM4E | |
| Hydrochloric Acid SCHEMBL27597122 | 0.81 | ALDH1A1 (0.53) | ALDH1A1NPSR1KMT2AMAPTKDM4E | |
| SCHEMBL15786407 | 0.76 | KMT2A (0.66) | ALDH1A1NPSR1KMT2AMAPTKDM4E | |
| SCHEMBL17518817 | 0.76 | KMT2A (0.61) | ALDH1A1NPSR1KMT2AMAPTKDM4E | |
| SCHEMBL16144650 | 0.76 | ALDH1A1 (0.54) | ALDH1A1NPSR1KMT2AKDM4ENOTUM | |
| SCHEMBL8540440 | 0.74 | ALDH1A1 (0.58) | ALDH1A1NPSR1KMT2AMAPTKDM4E | |
| SCHEMBL14242848 | 0.74 | ALDH1A1 (0.58) | ALDH1A1NPSR1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104086485-B | Prepare the method for poly-substituted quinoline type aromatic ring pyridine derivate | TSINGHUA UNIVERSITY (CN) | 2016-03-30 | — | — | CN | disclosed |
| CN-104086485-A | Method for preparing multi-substituted quinoline-type aromatic ring pyridine derivatives | UNIV TSINGHUA | 2014-10-08 | — | — | CN | disclosed |