Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28811499 | 0.85 | MAPT (0.35) | MAPTHCAR1ALDH1A1TDP1MEN1 | |
| SCHEMBL545054 | 0.81 | MAPT (0.47) | MAPTALDH1A1POLBTDP1MEN1 | |
| SCHEMBL4451596 | 0.80 | TSHR (0.41) | MAPTTDP1MEN1KMT2AATM | |
| SCHEMBL10589808 | 0.74 | ALDH1A1 (0.40) | ALDH1A1PTPN1MEN1KMT2AATM | |
| SCHEMBL30716857 | 0.73 | CA1 (0.35) | MAPTALDH1A1POLBTDP1KMT2A | |
| SCHEMBL3363981 | 0.72 | GRM4 (0.39) | MAPTALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL31560449 | 0.72 | GRM4 (0.39) | MAPTALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL6351831 | 0.72 | PTPN1 (0.53) | MAPTALDH1A1POLBTDP1PTPN1 | |
| SCHEMBL4588874 | 0.71 | CA1 (0.48) | MAPTALDH1A1POLBTDP1MEN1 | |
| SCHEMBL29863822 | 0.71 | CA1 (0.48) | MAPTALDH1A1POLBTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113185404-B | 1, 2-biaxial chiral biaryl compound and preparation method and application thereof | 武汉大学 | 2022-08-05 | — | — | CN | disclosed |